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1 was modeled into the binding site in COOT via structural alignment with 9CD8 (Chain A), and the structure was subsequently energy minimized prior to docking

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In addition, because of different drug bioavailability and absorption, SIBO has conflicting effects on intestinal symptoms of PD with different pharmacological interventions (Gibson and Barrett, 2019

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Because first year height velocity data suggests that the impact of rhIGF-1 among SPIGFD patients is less pronounced than rhGH for GH-deficiency (rhIGF-1: 6.9 [6.5, 7.2] cm/year [n = 144] vs rhGH: 8.67 [7.5, 9.9] cm/year [n = 465]) [14, 60], some HCPs may not perceive rhIGF-1 as beneficial enough for SPIGFD

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