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10.1073/pnas.1902452116 [DOI] [PMC free article] [PubMed] [Google Scholar] Yik MY, Azlan A, Rajasegaran Y, Rosli A, Yusoff NM, Moses EJ (2021) Mechanism of human telomerase reverse transcriptase (hTERT) regulation and clinical impacts in leukemia

Upregulation of Growth Factors Research published in the Journal of Peptide Science demonstrates that GHK-Cu stimulates the production of key growth factors including: Vascular Endothelial Growth Factor (VEGF) improves blood vessel formation Nerve Growth Factor (NGF) supports neural repair TGF-1 drives fibroblast activity and wound healing 3

PMID 16919017

For unregulated peptides, however, theres simply not enough evidence to say if theyre safe or not

It also modulates extracellular matrix turnover by restoring the balance between metalloproteinases (MMPs) and their tissue inhibitors (TIMPs)

GHK can be incorporated into topical gels, used in dermal patches, and collagen membranes, as well as being administered orally in liposomes and other carriers