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The last decade has seen a burgeoning research effort aimed at identifying genetic factors, phenotypical manifestations, biomarkers, and a pattern of imaging alterations, which would herald the onset of bipolar illness

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Early programmes, institutional studies, and preclinical model work examined how the compound class might influence receptor signalling, cellular adaptation, or tissue-level response patterns under controlled conditions

Methylation-directed acetylation of histone H3 regulates developmental sensitivity to histone deacetylase inhibition

26 LiH.Rodrguez-NietoG.ChalaviS.SeerC.MikkelsenM.EddenR

J Pharmacol Exp Ther 312:1926 McCance RA, Widdowson EM, Moran T, Pringle WJS, Macrae TF (1945) The chemical composition of wheat and rye and of flours derived therefrom