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This temporal regulation of autophagy genes promotes A degradation through the activation of astrocytic autophagy, whereas the pharmacological inhibition of autophagy exacerbates mitochondrial dysfunction and oxidative stress, ultimately leading to astrocyte death

A healthy diet needs to include moderate amounts of histamine, but too much of the compound can lead to chronic inflammation and other serious health conditions

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Supplementation with 300-600 mg/day has been shown to increase intracellular glutathione levels by 30-70% in cell culture and animal studies, with more modest increases in human trials (Suh et al., Proc Natl Acad Sci, 2004) [25]

Evidence of Heterogeneous and Variable Myelin Repair in MS Patients Observations of postmortem tissues from MS patients long ago raised the possibility of spontaneous myelin repair in humans (Prineas and Connell, 1979

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