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In addition to the insights into Fabry disease mechanisms obtained from HEK cell models, human umbilical vein endothelial cells (HUVECs) represent a meaningful tool for Fabry disease modeling since endothelial cells are known to be severely affected in Fabry disease [58]

The anticonvulsant drug vigabatrin is an irreversible inhibitor of GABA-T, and there is convincing evidence that it is effective in attenuating anxiety symptoms (513)

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Maintaining balanced levels of L-glutathione is crucial for both efficient detoxification and healthy cells