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Potential compounds Numerous preclinical studies testing mitochondria targeted compounds have indicated that the direct delivery of mitochondrial drugs to the brain is achievable through the intranasal route (Table 1)

Inazu M, Matsumiya T (2008) Physiological functions of carnitine and carnitine transporters in the central nervous system

Arch Pharm Res 46(4):339359

As the substrate-recognition component of the SCF (SKP1CUL1F-box protein) ubiquitin ligase complex, FBXL5 targets IRP2 for proteasomal degradation

Smad2 and 3 transcription factors control muscle mass in adulthood

Somatic genomic changes in single Alzheimers disease neurons