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This initiative builds upon a wide array of existing projects within Caput Mundi, which includes efforts led by Rome's municipal government and initiatives promoted by the Ministry of Culture

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168 Consequently, upregulation of Bmal1 expression may lead to elevated bone morphogenetic proteins (Bmp2) transcription through increased Inhibitor of DNA binding 1 ( Id1 ), RUNX2 , and Ocn expression, effectively promoting osteoblast differentiation

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While these benefits are promising and supported by animal studies, it's important to note that human clinical data is limited

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