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As to the aches and pains, breathlessness etc, this could be due to B12 needing potassium to build RBC, so I would check out low potassium symptoms and eat a banana or maybe two until you have fathomed it out

Ive found that patients who experience these side effects simply reduce the dosing and frequency of their B12 the symptoms usually resolve

Used appropriately, Vitamin B12 can help improve energy in patients who are low or trending low-normal relative to their needs

Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine