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Neurotherapeutics 7 , 452470 (2010)

Tucker S, Zhang M, Dong L, Mohan R , Kuban D, Thames H

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Its comprised of three amino acids: glycine, cysteine, and glutamine which is naturally produced by the liver and by neurons in the central nervous system

This review synthesizes current evidence on the molecular and cellular mechanisms underlying metformins glycemic control and cardiovascular benefits, highlighting both AMPK-dependent and AMPK-independent pathways