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Additionally, pulmonary metastasis was effectively inhibited, with virtually no metastatic tumor nodules observed (Fig

Pharmacological activation of NQO1 increases NAD + levels and attenuates cisplatin-mediated acute kidney injury in mice

References Bridges, C

Digestive health

[DOI] [PMC free article] [PubMed] [Google Scholar] 324.Shi M

Moreover, napabucasin is bioactivated directly by the tricarboxylic acid (TCA) cycle enzyme, 2-oxoglutarate (-ketoglutarate):acceptor oxidoreductase (OOR), leading to futile redox cycling and sustained generation of bactericidal levels of endogenous ROS