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45 The DNA damage can activate DNA repair processes including poly(ADP-ribose) polymerase (PARP), which may accelerate cell death by excessive consumption of nicotinamide-adenine dinucleotide (NAD)

doi: 10.3389/fphar.2020.00833 222

Moreover, previous quantitative phosphorylation analysis showed cell cycle-dependent in vivo phosphorylation of FZR1 at five N-terminal serine residues, including Ser32, 36 and 151 (ref

After reviewing the scientific literature and debating on key clinical issues, the EWG arrived at a 7-point management strategy that physicians could use in their clinical practice