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For localized joint or tendon issues, subcutaneous injection near the injury site delivers high local concentrations while also providing systemic distribution

Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans

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In accelerating wound healing, curcumin inhibits TGF-1/Smad7 axis, while it induces TGF-3

In these conditions, high mutation rates combined with selective pressure from single-agent therapy rapidly lead to resistant strains, necessitating concurrent use of agents with different mechanisms of action