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Minor changes in the setpoint of the axis caused by programming of the fetus exposed to intra-uterine growth retardation may predispose the individual for poor linear growth and later metabolic disease, insights that the pediatrician should be aware of and consider in order to improve health and prevent later disease

The search covered terms such as celiac, coeliac, comorbid*, complicat*, epidemiolog*, cohort, case-control, hazard model*, either alone or in combinations (see Supplementary Information for a detailed description)

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