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The CM11-CM13 showed significant changes in gene expression related to glutathione metabolism, indicating that glutathione plays a crucial role not only in the detoxification of reactive oxygen species (ROS) during stress responses but also in the regulation of redox signaling, gene expression, and cellular defense mechanisms (Fig

Recognizing the widespread impact of Cd pollution on both human health and the environment, comprehensive strategies, including stricter regulations and effective remediation methods, are essential to address the economic repercussions associated with Cd exposure

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Nonetheless, all doses consistently induced gut microbiota changes, oxidative stress and liver injury

These innovative uses san ART, fertility preservation strategies, and integrative approaches combining antioxidants with cutting-edge biomedical interventions, opening new avenues for improving male reproductive outcomes

Methods Ethics statement All animal work was done in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals of the National Institutes of Health and university regulations