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L., Staley, K

The main factors that are generally associated with elevations of homocysteine are nutritional deficiency, particularly related to folate metabolism, mutations of the enzymes MTHFR and CBS (Aguilar)

doi:10.4088/JCP.11m07139

This pro-oxidant effect is especially relevant in malignant cells, which often already exist under elevated basal oxidative stress

Pan J, Li Z, Dai S, Ding H, Wang Q, Li X et al (2020) Integrative analyses of transcriptomics and metabolomics upon seed germination of foxtail millet in response to salinity

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