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Targeting HSPs in autoimmune diseases HSP90 inhibition and inflammatory control HSP90 inhibitors have shown notable immunomodulatory activity in preclinical autoimmune models, consistent with the role of HSP90 in stabilizing signaling proteins that amplify immune activation

Essential components include monitoring for disease activity, disease progression, growth, and drug side effects (Tables 5 and 7) [29, 42, 50, 97, 133,134,135]