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Rare ATG7 genetic variants predispose patients to severe fatty liver disease

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Membrane phospholipids containing oxidizable polyunsaturated fatty acids (PUFAs) are primary targets for peroxidation, which can be initiated via enzymatic routes involving lipoxygenases or non-enzymatic mechanisms propelled by reactive oxygen species (ROS)

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The pancreas, another vital organ in the digestion process, can sometimes be affected by gallbladder disease