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2,20-22 Epidemiological studies fall into four categories based on the TB outcome they consider: the first section (Smoking and mortality from TB) reviews what is known about the association between TB mortality and smoking, the second section (Smoking and active TB) reviews the association between development of TB disease and smoking, the third section (Smoking and tuberculin skin test reactivity) reviews the association between infection with M

This is based on the assumption that tobacco smoking is overwhelmingly the most important cause of lung cancer, and that the incidence of this disease in the absence of smoking would be more or less the same in all populations, so that contemporary incidence (or mortality) rates from lung cancer simply reflect the cumulative exposure of a particular population to tobacco smoking

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And then the 1950s rolled aroundthe decade the controversy began