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Oxidative Stress Cigarette chemicals can trigger oxidative stress

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Kadowaki, J., Impact of total vending machine restrictions on US young adult smoking, Nicotine and Tobacco Research 18(11): 2092-2099, November 2016

Irritability can present as affective lability, characterized by rapid mood shifts from pleasant to irritable or angry states, which is a significant predictor of bipolar episodes 9

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