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Your Body Immediately After Vaping an E Cigarette When nicotine from a cigarette reaches your brain, it releases dopamine, the chemical that makes you feel good for a short time. This is what starts the addiction. Nicotine also changes other How Nicotine Hijacks Your Dopamine System: The Science of Why You Can't 'Just Stop' Smoking lights up brain's response differently in men and women Yale News Nicotine Addiction PMC Are Smokers Addicted To Dopamine? Smokefree
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