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The underlying mechanism is thought to involve nicotine interacting with nAChRs in the VTA, thereby raising dopamine levels in the striatum through the mesolimbic dopaminergic pathway, which dampens the effect of dopamine receptor blocking antipsychotics and consequently lessens extrapyramidal symptoms [20]

Smoking-related diseases kill approximately 438,000 people in this country each year

Where You CANT Legally Smoke Motor vehicles (including for passengers and when parked) Schools and school grounds are smoke-free zones Most parks, beaches, and boardwalks in NYC have banned smoking

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formaldehyde carcinogenic compound), poly aromatic hydrocarbons (PAHs), nicotine, phenol, furans, etc