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Because the outcome variable and the first mediator were dichotomous, and the focal predictor was an ordinal categorical measure, the mediation model was estimated in Mplus 8.3 using weighted least squares mean and variance adjusted (WLSMV) estimation with a probit link for endogenous categorical variables 23

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Even with more than 600 reports of seizures, the FDA did not make a public announcement until after it had investigated the possible link and after developed new labeling requirements to warn users of the rare risk of seizures associated with the drug

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