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Action on Smoking and Health (ASH), a British campaigning public health charity that works to eliminate the harm caused by tobacco, has published a landmark report on e-cigarettes acknowledging that they provide effective nicotine delivery and present little real-world evidence of harm. In addition, ASH supports regulation to ensure the safety and reliability of e-cigarettes but, in the absence of harm to bystanders, does not consider it appropriate to include e-cigarettes under smokefree regulations. I encourage you to read the 9-page report, which is available here

Plants produce an average of 20 leaves per plant with a nicotine content of 1%

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Food and Drug Administration says it's unclear whether e-cig users are inhaling potentially harmful chemicals

leaves it exposed to persistent cigarette-volume declines and domestic regulation