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According to the World Health Organization , COPD, which includes chronic bronchitis, is a leading cause of death worldwide, and smoking is the primary risk factor

[DOI] [PubMed] [Google Scholar] Mizes JS, Sloan DM, Segraves K, Spring B, Pingatore R, Kristeller J

It takes a toll on the nations economy, too: $289 billion is spent on health care and other financial losses associated with cigarettes annually