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For decades, international tobacco control and the WHO have focused their efforts on the prohibition of combustible cigarettes, the stigmatisation of smoking and, arguably, of smokers

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The nature of how this discomfort is experienced is in large part based on how far up the esophagus the stomach acid is regurgitated

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At a population level, given current trends a 5% cigarette smoking prevalence threshold will be reached much later in marginalized compared to less marginalized subpopulations