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Drug challenges can then be administered before ICSS sessions to determine whether the threshold for ICSS reinforcement is increased or decreased, which indicates a decrease or increase in drug reward, respectively (Negus and Miller, 2014)

Specifically, the oxidization products derived from smoking have been implicated in the impairment of mitochondria and endoplasmic reticulum 12,25

The authors have completed and submitted an ICMJE form for disclosure of potential conflicts of interest and they declare that they have no competing interests, financial or otherwise, related to the current work

B.HuangT.et al

Thats because everyone is different, and the appealing taste of many vapes might act like a trigger for some people, making them want to eat more