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This epigenetic reprogramming may underlie the immunosuppressive effects observed in cannabis smokers, as the transition from a Th 1 to a Th 2 response is associated with impaired cytokine production and diminished antimicrobial activity of AMs (75)

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Activated carbon filters saturate even faster, often requiring replacement every 3-4 months under constant smoke exposure

Cigarette packaging from the era ranged from civilian-branded boxes to military issue packets, often produced with reduced paper quality due to material shortages