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Overall, the evidence supporting the indirect functional benefits of exercise such as improvements in muscle strength, endurance, mobility, and quality of life is robust, whereas data on direct immunomodulatory or CNS-specific effects remain limited, highlighting the need for more translational studies to elucidate these mechanisms [132]

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HM Revenue and Customs figures published earlier this month suggest a record 1.9 billion illegal cigarettes were seized in the year to April, worth around 1.1 billion