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Some experts are concerned about how little is known about their potential health risks and about growing use by teenagers, fearing that a new generation will become hooked on nicotine

It is essential to exercise caution and choose products that undergo rigorous testing to minimize the risk of exposure to harmful chemicals [10]

Persistent symptoms beyond 10 days or severe pain with fever requires immediate medical evaluation to prevent complications

Other potential adverse health effects of ST may include toxicity of the immune, reproductive and/or cardiovascular systems.[6,10,11,12,13] Cardiovascular disease (CVD) is the leading cause of death worldwide, responsible for over 17 million deaths globally and tobacco has been estimated to directly cause 10% of all CVD worldwide.[14,15,16] The epidemiological evidence on cigarette smoking in relation to CVD is compelling, but the relationships between CVD and smokeless types of tobacco, is limited and remains uncertain