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Human lung tumor tissue specimens The treatment naive tissue specimens from 121 patients with EGFR WT NSCLC who have received EGFR TKI treatments (Supplementary Table 1) were obtained following the guidelines approved by Institute of Research Board Committee at China Medical University Hospital (DMR101-IRB1-120), and written informed consent was obtained from patients in all cases

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Market Overview and Direction The market for smoking-related products is defined by steady demand within a tightening regulatory environment