Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) cp PEG2 linker enhances water solubility

PEG2 linker enhances water solubility and provides spatial separation to minimize steric hindrance during binding interactions

68 Purity (HPLC) >= 95% Physical Appearance Orange solid Optical Properties Abs/Em Maxima: 553/580 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

758 Purity (HPLC) >= 95% Solubility DMSO

403 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(NCCOCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-PEG2-C2-azide Synonyms Thalidomide-4'-O-acetamido-PEG2-C2-azide CAS Number n/a Related CAS Molecular Formula C21H24N6O8 Molecular Weight 488

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) cp PEG2 linker enhances water solubilitySOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine