Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS

Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C79H112FN11O25 Molecular Weight 1634

176 Purity (HPLC) >= 95% Solubility DMSO

546 SMILES OCCOCCOCCOCCOCCOCC#CC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-PEG3-OH Synonyms Thalidomide-4'-O-acetamido-PEG3-OH CAS Number n/a Related CAS Molecular Formula C21H25N3O9 Molecular Weight 463

high extinction coefficient

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload