Trametinib Size:5mg S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5

S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5 Related CAS Molecular Formula C32H46N4O9S Molecular Weight 662

562 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCOCCOCCOCCN=[N+]=[N-])C1=CC=C(O)C=C1O2 Purity (HPLC) 98% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only

Product Name Phthalimidinoglutarimide-C6-OH Synonyms Phthalimidinoglutarimide-4'-C6-OH CAS Number n/a Related CAS Molecular Formula C19H24N2O4 Molecular Weight 344

333 SMILES BrCCOCCOCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

It can also be used for the synthesis of PROTACs based on Trametiglue

Trametinib Size:5mg S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5Trametinib (GSK1120212; JTP 74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib binds KRS MEK and disrupts RAF MEK. Product Name Trametinib Synonyms CAS Number 871700 17 3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615. 404 SMILES CN1C(=O)C(C)=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC1=C(F)C=C(I)C=C1)C1=CC(NC(C)=O)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO, DMF