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FIGURE 3 FIGURE 4 For between-group comparisons in smokers, we observed significant brain region atrophy in the subgroup of heavy smokers compared to light smokers, mainly in GM areas of precuneus, inferior frontal gyrus, insula, STG and cerebellum anterior lob, and in WM areas of cerebellum anterior lobe ( Table 4 )

While 54.9% stated they had not observed such behavior, 7.4% selected a less specific option (more than once), which may warrant refinement in future survey designs to improve clarity regarding the context, frequency, or location of smoking behavior

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