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have demonstrated that mice fed with WD develop a profound dysbiosis leading to immune dysfunction resulting in: a) decrease in mucous secretion, b) loss of secretive IgA function, c) inhibition of Treg cells producing IL-10, d) impaired barrier integrity, e) loss of immune homeostasis, that is the premise for the future onset of ICD (autoimmune and allergy) (48)

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Moreover, key challenges, such as single-target limitations and the complexity of metabolic regulatory mechanisms, restrict the development and application of new drugs

The levels of labeled propionylcarnitine in fasting plasma were approximately 60% of those in fed plasma (Fig

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Glutathione helps convert toxins into water-soluble compounds, making it easier for the body to excrete them (Anderson et al., 2021)