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While early research and anecdotal evidence suggest positive results, its long-term safety profile remains unclear due to limited human clinical trials

For many dog and cat vaccines, the recommended booster interval has been one year, although, for some agents, a longer interval has been established, such as feline panleukopenia vaccines and some rabies vaccines

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However, animals that are largely herbivorous yet still classify as non-ruminants rely on another method of getting sufficient vitamin B12 they cannot get from their diet, and that is coprophagia or eating their own poop

However, these vaccines have lower neutralizing activity against variants, especially the Beta and Delta