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Curcumin, extracted from Radix curcumae, reduces the expression of COX-2, 5-lipoxygenase mRNA and protein in the hippocampal neurons of epileptic rats through the regulation of free radicals and carbon monoxide synthase and improves the anti-oxidative stress effect, hippocampal neuron damage, and cognitive function of pilocarp-induced epileptic in experimental rats (Yang et al., 2018)

Reestablishing the cellular metabolic homeostasis in SARS-CoV-2 infection and COVID-19 disease especially in the lungs, could become paramount to balance altered innate and adaptive immunity and cell function and reduce morbimortality (Hsu et al., 2022

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Clinical studies show that sublingual B12 is as effective as intramuscular B12 injections as it is absorbed via the mucous membranes in the mouth, bypassing the digestive tract

Jacobsen et al., 2012)

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