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Liu X, Luo J, Chen J, Huang P, He G, Ye X, Su R, Lao Y, Wang Y, He X, Zhang J

Adaptation of N -methyl-D-aspartate (NMDA) receptors following antidepressant treatment: implications for the pharmacotherapy of depression

Chapter 8quantification and analysis of proteins In: ShenC-H, editor

When stratified by administration route, the average percentage reductions were: Intramuscular (IM): 48.3% Sublingual: 30.7% Oral: 30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects

And for decades, neuroscience offered precious few tools to intervene once this cascade began