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Int Immunopharmacol 86:106689

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demonstrated that MIRI in mice resulted in mitochondrial iron accumulation, which triggered lipid peroxidation and subsequently led to heart failure and myocardial remodeling induced by cardiac I/R [141]

Recombinant FcRn Truncated soluble and Glutathione S-transferase (GST) tagged human FcRn lacking the transmembrane domain (hFcRn-GST) was produced in HEK293E cells and purified on a GSTrap column (Cytiva Life Sciences) 67

However, its use as an effective oral supplement has been limited due to poor absorption when taken traditionally

Listed among some of the more severe indicators of a B12 deficiency are cognitive disorders, depression, paranoia or even a loss of the senses of taste and smell