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While A and Tau have been the main subjects of prior study, new data emphasizes mitochondrial breakdown and the ensuing oxidative stress as early, predictable events in AD pathogenesis

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After absorption, ergothioneine circulates in the blood and accumulates in target tissues via OCTN1 transporters

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These would include, for example, antacid medications that inhibit the bodys production of stomach acid, anti-cholesterol medications that block the production of cholesterol, and selective serotonin reuptake inhibitors (SSRIs) that block the uptake of serotonin to treat depression

Need for Robust Human Clinical Trials: Large-scale, randomized, placebo-controlled human clinical trials are indispensable