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We found that the levels of CXCL10 and its downstream effectors, p-JNK, COL1A1, and p-AKT, significantly increased in M38 or B16 group, WCV significantly reduced their levels close to control in VM38 or VB16 group, and PD-1 had no obvious impacts in PM38 or PB16 group (Fig

Nicotinamide riboside supplementation alleviates testicular aging induced by disruption of Qprtdependent NAD + de novo synthesis in mice

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Zhang M, Gao H, Zheng J, et al

In summary, our results indicate substantial changes in ECM composition in KO cells, which may influence the direction of endoderm differentiation

Magnetic resonance classification of lumbar intervertebral disc degeneration