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Trimethylamine n-oxide promotes vascular inflammation through signaling of mitogen-activated protein kinase and nuclear factor-B

Timing: Split into two doses per day, ideally taken with carbohydrate-containing meals to enhance absorption and uptake into muscle cells

In addition, in further clinical research, it was found that taking berberine orally can reduce plaque score and TMAO content in feces and plasma, showing its efficacy in regulating TMAO to prevent and treat AS (Ma et al., 2022)

Vitamin A, in the form of retinyl palmitate, regulates the proliferation and differentiation of keratinocytesthe primary cells that make up the outermost layer of the skin

In: Campbell M, Walsh P (eds)