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Gut microbiota dysbiosis in depressed women: the association of symptom severity and microbiota function

Li M, Cui H, Deng H, Deng Y, Yin S, Li T

Carpenter DO

Conclusions and perspectives By integrating mechanistic insights and disease-specific evidence, this review delineated how ATFs orchestrate macrophage development, survival, migration, phagocytosis, activation, cytokine secretion and polarization and how these regulatory axes converge to shape macrophage-driven pathology in infectious, inflammatory, metabolic, oncologic and neurodegenerative settings

Nrf2 plays a key role in the hepatoprotective effects of chlorogenic acid, which alleviates APAP-induced liver injury by regulating heat shock protein 60 (HSP60)-initiated liver inflammation (Wei M

RBCs are particularly susceptible to oxidative stress due to the lack of nuclei needed for protein synthesis, the absence of mitochondria capable of supplying NADPH outside of the PPP, and a high iron content that drives Fenton chemistry 8