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The mononuclear phagocyte system, consisting of a number of cell types including monocytes and macrophages, is part of both humoral and cell-mediated immunity and has an important role in defence against microorganisms, including mycobacteria, fungi, bacteria, protozoa and viruses

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth

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The predominant LMW thiol in Gram-negative bacteria is glutathione (GSH

doi: 10.1183/09031936.97.10071535 16 De FloraS.BalanskyR.La MaestraS

The findings were attributed to the patients status of extensive or ultrarapid metaboliser of CYP2D6 that was able to overcome the inhibition of CY2D6 and 3A4 activity promoted by ritonavir